| √ |
Lecture 1 (Xray)
|
|
Overview, and Symmetry
|
|
| √ |
Lecture 2
|
|
Waves and wave addition
|
|
| √ |
Lecture 3
|
|
Crystal planes, Bragg's law
|
|
| √ | Lecture 4 |
| Laue conditions, Ewald sphere, data collection | |
| √ | Lecture 5 |
| Data collection, Patterson space, molecular replacement | |
| √ | Lecture 6 |
| Heavy atom isomorphous replacement. Harker diagrams. | |
| √ | Lecture 7 |
| Anomalous dispersion, multiwavelength method, phase probability distribution, figure of merit | |
| √ | Lecture 8 |
| Electron density maps. R-factor. Free R-factor. Omit maps. 2Fo-Fc. | |
| √ | Lecture 9 |
| Term Project. Coot. Real space manual refinement. Rotamers. Waters. | |
| √ | Lecture 10 |
| Some review. Model validation. Ramachandran plot. PDB. | |
| √ | Lecture 11 |
go to Webex
| Xray lasers, Laue photography, and electron diffraction. | |
| √ | Lecture 12 |
go to Webex
| Do-It-Yourself review session. | |
| √ | Lecture 13 |
go to Webex
| More review session. | |
| √ | Fall 2021 Lecture 12 |
| Cryo EM, MicroED, Laue photography and XFEL. | |
| √ | Fall 2021 Review session |
| DIY review session. | |
| Also see videos on Blackboard |
